(19 customer reviews)



Night Cream. Fine lines & wrinkles.

The SkinCeuticals Retinol 0.5 is a refining night cream enriched with 0.5% pure retinol that is specifically indicated to help reduce the appearance of fine lines, wrinkles and dark spots. Retinol 0.5 contains 0.5% pure retinol. SkinCeuticals Retinol 0.5 can be used either as a corrective treatment on its own, or to accelerate the effects of additional corrective products or treatments.

Size: 30 ml

Not to be used if you are pregnant or breast feeding or planning on falling pregnant!

Add to Cart

Skin results and statements are based on clinical trials performed by the brand and individual results may vary.



How to use

How to use

Apply a pea sized amount to the face and neck after cleansing and before applying any other night creams and/or serums. It is recommended to wait 30 minutes before applying any other ingredient to the skin after SkinCeuticals Retinol 0.5 application. It is recommended to introduce the retinol slowly to ones skincare regime: once a week for 4 weeks, twice a week for 4 weeks, then 3 times a week. A broad-spectrum sun protection is a must when retinol is part of your skincare regimen.

Features & Benefits

Features & Benefits

Retinol 0.5 has one of the highest concentrations of pure retinol available in skincare products and is enhanced with the latest stabilization and delivery technologies. An innovative system captures and stabilizes retinol without enclosing it to help ensure the full dosage is slowly and evenly released.

A unique delivery system based on the skin’s natural lipid structure helps carry high concentrations of retinol to the target site in the skin. Major benefits include:

  1. Diminishes the appearance of fine lines and wrinkles
  2. Reduces visible age spots
  3. Minimizes pore size, to refine skin texture
  4. Corrects blemishes associated with problematic skin
  5. Compresses the stratum corneum
  6. Thickens the dermis (through collagen synthesis)


  • Research has clearly shown that retinol is less irritating than retinoic acid and more suitable for topical application


  • A potent anti-irritant, derived from the chamomile plant that helps soothe and calm skin.


  • Tolerance from person to person varies
  • Photosensitizing: increased sensitivity to the sun
  • Accutane users (wait 6-12 months after stopping use of Accutane)
  • Pregnant or lactating
  • Discontinue use for at least 5 days before peels or laser treatments
  • Overuse may result in red or excessively flaking skin

Designed for efficacy and stability, SkinCeuticals’ Retinol is formulated with high concentrations of pure retinol and enhanced with stabilisation and delivery technologies to help ensure effective absorption

Innovation 1

Unlike products that use traditional encapsulation technology, SkinCeuticals’ innovative delivery system captures and stabilises Retinol

Innovation 2

‘SkinCeuticals’ Retinol products contain an innovative delivery system based on the skin’s lipid structure to help ensure absorption

Key Ingredients

Key Ingredients

0.5% Retinol / Bisabolol

Full ingredient list:

Aqua / Water / Eau, Propanediol, Dimethicone, Cetearyl Ethylhexanoate, Alcohol Denat., Dipropylene Glycol, Ammonium Polyacryloyldimethyl Taurate, Allyl Methacrylates Crosspolymer, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Hydrogenated Lecithin, Isohexadecane, Retinol, Phenoxyethanol, Caprylyl Glycol, Polysorbate 20, Isopropyl Myristate, Sodium Citrate, Boswellia Serrata Gum, Polysorbate 80, Dimethiconol, Trisodium Ethylenediamine Disuccinate, Bisabolol, BHT, Sorbitan Oleate, Citric Acid, Propyl Gallate.

Reviews (19)

19 reviews for SKINCEUTICALS Retinol 0.5

  1. Chantal (verified owner)

    This retinol is amazing! I have sensitive skin and this is perfect on my skin, no irritation at all. My skin is smooth and I haven’t had a breakout since using this product.

  2. Iona (verified owner)

    Really brilliant and gentle enough for me – as long as I ease myself up to every second day. I did overdo it initially and even so I was ever so slight red and my face exfoliated unnoticeably – I could feel it and it was slightly itchy but not visible to anyone else. After a couple of days of this I felt I had a brand new, smooth and fresh face. Lovely.

  3. Bernice (verified owner)

    Very good product that definitely does what is says.

  4. Amy (verified owner)

    I’ve always thought this product was a fad but oh my word I’ve been wasting time – it is TOTALLY worth the hype! After just two weeks of use, my PIH is already lighter and the overall texture of my skin is far smoother. I was a bit nervous about the strength and have noticed my skin is a little on the dry side but other than that this has been the missing piece of my skincare routine!

  5. Rita (verified owner)

    Definitely works. My skin texture is amazing. No irritation either. I use it every second night. Alternating with glycolic acid. SkinCeuticals for the win!

  6. Deshni (verified owner)

    Its an amazing product, i have been using this product for almost 3 years, skin peels evenly after 3 days, reduces fine lines, no more breakouts and gives an even skintone. Worth it!

  7. Kirbashnee (verified owner)

    This product is amazing . It’s been a month since I started and my skin has improved so much in terms of texture and brightness
    I am in menopause and was experiencing dull, uneven skin with enlarged pores. This cream has made a huge difference

  8. DerryAnn (verified owner)

    This is a really great product. I use it twice a week as that’s all my skin can handle. I have seen a visible difference in my mild scarring caused by breakouts. You really only need to use a pea sized amount so the product lasts well.

  9. Rebecca (verified owner)

    A friend recommended this and I’m totally blown away ! Its definitely a game changer .❤️

  10. Sawleha (verified owner)

    This product has made such a visible difference to the overall appearance of fine lines, texture and blemishes on my face. When used in conjunction with other SkinCeuticals products, it really packs a punch and this tube lasts really long as well!

  11. Sindiswa (verified owner)

    Absolute game changer. This has made such a big difference to my skin. I suffer from hormonal acne and as a result I have a lot of blemishes and marks left from my breakouts. This product has helped with the appearance of blemishes on my skin as well as my pigmentation. A little goes a long way!!!!

  12. Perushka (verified owner)

    I started off the other way around in error with the 1% which was too strong as I was new to retinol. However the 0.5 % is perfect. I introduced the product slowly , once a week and then twice. I’ve started to see a difference with slight peeling but not terrible . This is a great product that feels light on the skin. I’m excited to see the improved results as I continue with the product.

  13. Gizella (verified owner)

    This is a potent Retinol and it is advisable to introduce it slowly into ones skincare routine. I have used Retinol from various other skincare brands, but I find that SkinCeuticals continues to provide the best results. I saw an improvement in the texture of my skin within 3 weeks. Excellent for fine lines and pigmentation. You only need a pea size of the product with every application, so it lasts long, which for me justifies the price. I specifically use this product to prepare my skin for in office treatments such as the Dermapen.

  14. Barbara (verified owner)

    Best retinol ever used!!

  15. Cleo (verified owner)

    I’ve tried other retinols but none like this one. I’ve been using this just a lil over 2 months and I have noticed an improvement in the texture of of my skin, blemishes,fine lines and l’m breaking out less. I have dry acne prone skin and this product has been helpful in shedding off the dead skin.

  16. Anri (verified owner)

    Another amazing product from SkinCeuticals ! By far the best retinol I have used , uses it 3 evenings a week and already see an improvement in fine lines and pigmentation . SkinCeuticals never disappoints !

  17. Zamahlase (verified owner)

    It’s been 2 weeks (alternating nights) since I started using this product, already seeing remarkable results on my skin. It has reduced the appearance of pore sizes and blemishes on my face. My skin is smoother and hydrated.

  18. Rispah (verified owner)

    I started with the Skinceuticals 0.3 retinol before slowly introducing my skin to 0.5 retinol. Despite my sensitive and acne-prone skin I have used Skinceuticals retinol for more than 2 years without problems . It has definitely reduced fine lines on my skin. I have tried cheaper brands of retinol but they break out my skin. I will stick to this brand of retinol.

  19. AldineB (verified owner)

    This product is extremely effective. My skin peels after a day or two but after that my skin feels smooth and clear. It has reduced my fine lines. I use it very sparingly, so the product will last for months.

Add a review
Shipping & Delivery

Main Centre

Delivered to your door within 1-2 working days after payment is confirmed with Standard Delivery.

Regional Area

Delivered to your door within 3-5 working days after payment is confirmed with Standard Delivery.

Remote Area

Delivered to your door within 5-7 working days after payment is confirmed with Standard Delivery.

Delivery Options

  • FREE Delivery: On orders above R 750.00
  • Delivery Fee R120.00: On orders below R 750
  • I want to collect? - Collections welcome at our Pretoria office.


Main Centres: Johannesburg, Cape Town, Pretoria.
Remember that weekends and public holidays are not work days.