(2 customer reviews)



Serum. Hyperpigmentation, erythema, uneven skin tone.

Phloretin CFis an antioxidant serum that delivers environmental protection while diminishing the appearance of discolouration. Ideal if you want your skin shielded from free radicals for a more radiant, even complexion

Size: 30 ml

In stock (can be backordered)

If you purchase this product you will earn 1716 SkinMiles Worth R171.60

Skin results and statements are based on clinical trials performed by the brand and individual results may vary.



How to use

How to use

Once daily, in the morning, apply directly after cleanse and tone. Using fingertips, apply 4-5 drops of Phloretin CF to face, neck, and chest. Follow with application of your recommended corrective product, moisturiser and SPF.

Features & Benefits

Features & Benefits

Derived from apples and the root bark of fruit trees including apple, pear, and grapefruit, Phloretin is a broad- spectrum molecule newly identified for its antioxidant properties and recently studied for use as a pigment- regulating and penetration-enhancing agent in the medical community. Additionally, it displays a wide range of bioactivities such as anticancer, antifungal, antibacterial, antiviral, and anti-inflammatory.

[quote author=”Dr Alek Nikolic”]”Phloretin CF™ represents a new class of preventive and corrective topical antioxidant treatment. This patent- pending breakthrough technology combines the broad-range power of Phloretin with vitamin C and Ferulic acid in a synergistic biodiverse formulation to divide and conquer sources of damage at every level of the skin.”[/quote]

Phloretin CF™ is a broad-spectrum treatment that protects  against not only free radicals,  but the range of other reactive molecules known  to cause damage and DNA mutations among the integral cell types.

Effect of vitamin C, ferulic acid, and phloretin (CFerPhlor) protection against ultraviolet (UV)-induced erythema. CFerPhlor or vehicle alone (control) were applied to back skin (2 mg/cm2) daily for 4 days. Skin was irradiated with solar-simulated UV 1×–5× minimal erythema dose (MED). Erythema was determined 1 day later.


For over a decade, SkinCeuticals has offered a variety of antioxidant treatments to combat environmental damage caused by reactive oxygen species.

Through continuous research and development, we strive to provide the most comprehensive solution to prevent and correct photodamage caused by oxidative stress. Phloretin CF:

  1. Prevents premature signs of aging
  2. Corrects existing photo damage, especially age spots
  3. Facilitates cellular repair
  4. Reconstructs the skin’s support structure.




Key Ingredients

Key Ingredients

Key Ingredients:


  • The body’s most important water-soluble antioxidant
  • Inhibits UVA and UVB radiation-induced damage
  • Photo protective capabilities
  • Promotes collagen synthesis
  • Anti-inflammatory properties



  • Comes from apples and the root bark of fruit trees including apple, pear, and grapefruit
  • Classified as a flavonoid known to prevent immunosuppression and for anti-inflammatory, antifungal, and anticancer properties
  • Accelerates cell turnover
  • Suppresses radiation-induced oxidative reactions
  • Slows the degradation of collagen
  • Increases the production of elastin
  • Maintains the integrity of the extra cellular matrix
  • Inhibits UV-induced melanogenesis



  • Ubiquitous plant antioxidant
  • Neutralizes free radicals known as “superoxide,” “hydroxyl radical” and “nitric oxide”
  • Suppresses radiation-induced oxidative reactions
  • Acts synergistically with other antioxidants, improving their potency
  • Absorbs UV (approved sunscreen in japan)
  • Anti-inflammatory properties
  • Easily absorbed by the skin
Reviews (2)

2 reviews for SKINCEUTICALS Phloretin CF

  1. Ursula

    Absolutely loved this. I got it as a sample when I ordered the cleanser. I was hooked from about day 2. My skin was brighter, plumper and very radiant. I’m still accumulating enough skinmiles to spoil myself with the full sized bottle. A definite buy again ❤️

    • Dr Alek Nikolic

      Hi Ursula thank you for the review it is appreciated and will go a long way in helping customers decide if they should purchase the Phloretin CF. You may be interested in the limited edition mini Phloretin CF 15 ml which is now available to purchase. If you are interested please follow this link: Phloretin CF 15 ml Limited Edition
      Kind regards Dr Alek

  2. Sally

    The best way to keep your skin healthy and protected. I’m not sure how it works, but it works. A little goes a long way.

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Delivered to your door within 5-7 working days after payment is confirmed with Standard Delivery.

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  • Delivery Fee R120.00: On orders below R 750
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